Zhouxi “Josie” Wang

Zhouxi “Josie” Wang

Graduate Student (2008-2013)

Current Institution

National Institutes of Health, Bethesda, MD

Undergraduate Institution

Donghua University, Shanghai, China

Research Projects

Computer-aided drug design for Human African Trypanosomiasis (HAT).

Molecular modeling methodology development for annotation of biochemical functions of enzymes in superfamilies.

Personal Interests

Yoga, traveling, history and new technology.

Conference Presentations

  • 2011 – Protein Society Conference, Boston, MA
  • 2010 – ACS National Meeting, Boston, MA
  • 2010 – ISMB Conference Boston, MA
  • 2009 – ASMS, Philadelphia, PA



The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing

Stefan O. Ochiana, Vidya Pandarinath, Zhouxi Wang, Rishika Kapoor, Mary Jo Ondrechen, Larry Ruben, and Michael P. Pollastri, European Journal Medicinal Chemistry62, 777-784 (2013)

Protein Function Annotation with Structurally Aligned Local Sites of Activity (SALSAs)

Zhouxi Wang, Pengcheng Yin, Joslynn S. Lee, Ramya Parasuram, Srinivas Somarowthu, and Mary Jo Ondrechen, BMC Bioinformatics14 (Suppl 3):S13 (2013)


Pharmacological Validation of Trypanosoma brucei Phosphodiesterases B1 and B2 as Druggable Targets for African Sleeping Sickness

Nicholas D. Bland, Cuihua Wang, Craig Tallman, Alden E. Gustafson, Zhouxi Wang, Trent D. Ashton, Stefan Ochiana, Gregory McAllister, Kristina Cotter, Anna P. Fang, Lara Gechijian, Norman Garceau, Rajiv Gangurde, Ron Ortenberg, Mary Jo Ondrechen, Robert K. Campbell, and Michael P. Pollastri, Medicinal Chemistry 54 (23), 8188-8194 (2011)


Desulfurization of Cysteine-Containing Peptides Resulting from Sample Preparation for Protein Characterization by MS

Zhouxi Wang, Tomas Rejtar, Zhaohui Sunny Zhou and Barry L. Karger, Rapid Communications in Mass Spectrometry, 24 (3):267-275 (2010)


TAT Peptide and Its Conjugates: Proteolytic Stability

Jacob Grunwald, Tomas Rejtar, Rupa Sawant, Zhouxi Wang, Vladimir P. Torchilin, Bioconjugate Chemistry, 20 (8): 1531–1537 (2009)


Facile preparation of pH-responsive gelatin-based core–shell polymeric nanoparticles at high concentrations via template polymerization

Youwei Zhang, Zhouxi Wang, Yansong Wang, Jiongxin Zhao and Chengxun Wu, Polymer, 48 (19): 5639-5645 (2007)


 A Way to Prepare Core-Shell Biocompatible Polymeric Nano-particles from Gelatin and Acrylic acid

Zhouxi WangYouwei Zhang, Yansong Wang, Jiongxin Zhao, Chengxun Wu, Journal of Macromolecular Science, 43 (11): 1779-1786 (2006)


pH Responsive Core-Shell Particles and Hollow Sphere Attained by Macro molecular Self-Assembly

Youwei Zhang, Ming Jiang, Jiongxin Zhao, Zhouxi Wang, Hongjin Dou, Daoyun Chen, Langmuir, 21 (4): 1531-1538 (2005)